Models for sensory neurons of dorsal root ganglia and stress urinary incontinence
نویسندگان
چکیده
منابع مشابه
Models for sensory neurons of dorsal root ganglia and stress urinary incontinence.
AIMS To discuss (1) animal models for investigating bladder afferent pathways from the spinal cord to the brain and (2) animal models of stress urinary incontinence (SUI) with a special emphasis on functional and histopathological characteristics of each model. METHODS Literature review of spinal mechanisms of bladder afferent pathways and animal models of SUI. RESULTS Electrophysiological ...
متن کاملDistribution and neurochemical characterization of sensory dorsal root ganglia neurons supplying porcine urinary bladder.
UNLABELLED Pig has been used recently as an animal model for studying diseases of human urinary tract, however, the sensory innervations of urinary bladder in this species has not been yet described. OBJECTIVE The present study was aimed at neurochemical characterization of sensory neurons of dorsal root ganglia (DRGs) supplying porcine urinary bladder. METHODS Retrograde tracer Fast Blue (...
متن کاملcaspase-mediated apoptosis in sensory neurons of cultured dorsal root ganglia in adult mouse
objective: sensory neurons in dorsal root ganglia (drg) undergo apoptosis after peripheral nerve injury. the aim of this study was to investigate sensory neuron death and the mechanism involved in the death of these neurons in cultured drg. materials and methods: in this experimental study, l5 drg from adult mouse were dissected and incubated in culture medium for 24, 48, 72 and 96 hours. fresh...
متن کاملPaclitaxel-Resistant Neurons in Dorsal Root Ganglia
Paclitaxel is an antineoplastic drug, and its usage is often limited by severe peripheral polyneuropathy characterized by symptoms in remote extremities. It is suggested that subpopulations of dorsal root ganglion (DRG) neurons are impacted functionally and/or structurally. In this study, the neurotoxic effect of this drug in cultured rat DRG neurons was analyzed by measuring their neurite leng...
متن کاملRhoA is dispensable for axon guidance of sensory neurons in the mouse dorsal root ganglia
RhoA, a member of the Rho family small GTPases, has been shown to play important roles in axon guidance. However, to date, the physiological function of RhoA in axon guidance events in vivo has not been determined genetically in animals. Here we show that RhoA mRNA is strongly expressed by sensory neurons in the developing mouse dorsal root ganglia (DRG). We have deleted RhoA in sensory neurons...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurourology and Urodynamics
سال: 2011
ISSN: 0733-2467
DOI: 10.1002/nau.21138